Chemical and Biomedical Engineering

Dr. Moo-Yeal Lee Publications

Recent Peer-Reviewed Publications
  • Lee, D.W., Choi, Y.S., Seo, Y.J., Lee, M.Y., Jeon, S.Y., Ku, B.S., Kim, S.J., Yi, S.H., Nam, D.H., High-throughput screening (HTS) of anticancer drug efficacy on a micropillar/microwell chip platform, Analytical Chemistry, In revision (2013).
  • Kwon, S.J., Lee, D.W., Shah, D.A., Ku, B.S., Jeon, S.Y., Clark, D.S., Dordick, J.S., and Lee, M.Y., High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening, Submitted in Nature Communications (2013).
  • Lee, D.W., Yi, S.H, Jeong, S.H., Ku, B.S., Kim, J.G., and Lee, M.Y., Plastic pillar inserts for three-dimensional (3D) cell cultures in 96-well plates, Sensors and Actuators B, 177(1), 78-85 (2013) .
  • Zhang, H.Y., Lee, M.Y., Hogg, M.G., Dordick, J.S., and Sharfstein, S.T., High-throughput transfection of interfering RNA into a three-dimensional cell-culture chip, Small, 8(13), 2091-2098 (2012).
  • Kwon, S.J., Mora-Pale, M., Lee, M.Y., and Dordick, J.S., Expanding nature’s small molecule diversity via in vitro biosynthetic pathway engineering, Current Opinion in Chemical Biology, 16, 186-195 (2012).
  • Lee, M.Y., Dordick, J.S. and Clark, D.S., Metabolic enzyme microarray coupled with miniaturized cell-culture array technology for high-throughput toxicity screening, Methods in Molecular Biology, 632, 221-237 (2010).
  • Zhang, H.Y., Lee, M.Y., Hogg, M.G., Dordick, J.S., and Sharfstein, S.T., Gene delivery in three-dimensional cell cultures by superparamagnetic nanoparticles, ACS nano, 4(8), 4733-4743 (2010).
  • Fernandes, T.G., Kwon, S.J., Lee, M.Y., Diogo, M.M., Clark, D.S., Cabral, J.M.S., and Dordick, J.S., Three-dimensional cell culture microarray for high-throughput studies of stem cell fate, Biotechnology and Bioengineering, 106, 106-118 (2010).
  • Sukumaran, S.M., Potsaid, B., Lee, M.Y., Clark, D.S., and Dordick, J.S., Development of a fluorescence-based, ultra high-throughput screening platform for nanoliter-scale cytochrome P450 microarrays, Journal of Biomolecular Screening, 14(6), 668-678 (2009).
  • Park, T.J., Lee, M.Y., Dordick, J.S. and Linhardt, R.J., Signal amplification of target protein on heparin glycan microarray, Analytical Biochemistry, 383, 116-121 (2008).
  • Fernandes, T.G., Kown, S.J., Lee, M.Y., Clark, D.S., Cabral, J.M.S. and Dordick, J.S., On-chip, cell-based microarray immunofluorescence assay for high-throughput analysis of target proteins, Analytical Chemistry, 80, 6633-6639 (2008).
  • Lee, M.Y., Ramasubramanian, A.K., Sukumaran, S., Hogg, M., Clark, D.S. and Dordick, J.S., Three-dimensional cellular array chip for microscale toxicology assay, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(1), 59-63 (2008).
  • Kwon, S.J., Lee, M.Y., Ku, B.S., Sherman D.H. and Dordick, J.S., High-throughput, microarray-based synthesis of natural product analogues via in vitro metabolic pathway construction, ACS Chemical Biology, 2(6), 419-425 (2007).
  • Lee, M.Y. and Dordick, J.S., High-throughput human metabolism and toxicity analysis, Current Opinion in Biotechnology, 17, 619-627 (2006).
  • Lee, M.Y., Clark, D.S. and Dordick, J.S., Human P450 microarrays for in vitro metabolite toxicity analysis: Toward complete automation of human toxicology screening, Journal of the Association for Laboratory Automation, 11(6), 374-380 (2006).
  • Lee, M.Y., Park, C.B., Clark, D.S. and Dordick, J.S., Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 102(4), 983-987 (2005).
  • Lee, M.Y., Hong, K.J., Kajiuchi, T. and Yang, J.W., Synthesis of chitosan-based polymeric surfactants and their adsorption properties for heavy metals and fatty acids, International Journal of Biological Macromolecules, 36(3), 152-158 (2005).
  • Lee, M.Y., Srinivasan, A., Ku, B.S. and Dordick, J.S., Multienzyme catalysis in microfluidic biochips, Biotechnology and Bioengineering, 83(1), 20-28 (2003).
  • Srinivasan, A., Wu, X.Q., Lee, M.Y. and Dordick, J.S., Microfluidic peroxidase biochip for polyphenol synthesis, Biotechnology and Bioengineering, 81(5), 563-569 (2003).
  • Lee, M.Y. and Dordick, J.S., Enzyme activation for nonaqueous media, Current Opinion in Biotechnology, 13, 376-384 (2002).