Cell and Tissue Engineering Lab

Publications

http://scholar.google.com/citations?user=nwqrk4YAAAAJ&hl=en&oi=ao

BOOKS
  1. Kothapalli CR & Ramamurthi A.
    Elastic Fiber Matrices: Biomimetic Approaches to Regeneration and Repair.
    Taylor & Francis Group, CRC Press, To be Published in Summer 2015.

 

PEER-REVIEWED JOURNAL PUBLICATIONS (* as corresponding author)
  1. Sameera T, Farrell K, Lee M-Y, Kothapalli CR*. Sensitivity of neural stem cell survival, differentiation and neurite outgrowth within 3D hydrogels to environmental heavy metals. Applied In Vitro Toxicology, 2015, Submitted.
  1. Farrell K, Weiss RA, Kothapalli CR*. Injectable uncrosslinked biomimetic hydrogels as candidate scaffolds for neural stem cell delivery. ACS Biomaterials Science and Engineering, 2015, In submission.
  1. Joshi J, Kothapalli CR*. Nanofibers based drug design and delivery for myocardial regeneration. Current Pharmaceutical Design, 2015, 21(15): 2006-20.
  1. Simmers P, Gishto A, Vyavahare N, Kothapalli CR*. Nitric oxide stimulates matrix synthesis and deposition by adult human aortic smooth muscle cells within 3D cocultures. Tissue Engineering Part A, 2015, 21(7-8):1455-70.
  1. Gishto A, Farrell K, Kothapalli CR*. Tuning composition and architecture of biomimetic scaffolds for enhanced homing and matrix synthesis by cardiomyocytes. J Biomed Mater Res Part A, 2015, 103(2): 693-708.
  1. Kothapalli CR*, Honarmandi P. Theoretical and experimental quantification of the role of diffusive chemogradients on neuritogenesis within 3D collagen scaffolds. Acta Biomaterialia, 2014, 10: 3664-3674.
  1. Srinivasan P, Zervantonakis IK, Kothapalli CR*. Synergistic effects of 3D ECM and chemogradients on neurite outgrowth and guidance: A simple modeling and microfluidic framework. PLoS One, 2014, 9(6): e99640 (15 pages).
  1. Singh T, Kothapalli CR, Varma D, Nicoll SB, Vazquez M. A haptotaxis neutral biomaterial to examine motility of CNS-derived tumor cells. J Biomaterial Applications, 2014, 29(3): 433-41.
  1. Kothapalli CR*, Kamm RD. 3D matrix microenvironment for targeted differentiation of embryonic stem cells into neural and glial lineages. Biomaterials, 2013, 34: 5995-6007.
  1. Farrell K, Kothapalli CR*. Tissue Engineering approaches for motor neuron pathway regeneration. Journal of Regenerative Medicine, 2012, 1:2. (15 pages).
  1. Tharin ST, Kothapalli CR, Pasquina L, Ozdinler PH, Chung S, de Valence S, Varner J, Macklis JD, Kamm RD. A novel microfluidic device to investigate axon targeting in small numbers of purified cortical projection neurons. Integrative Biology. 2012, 4: 1398-1405. (equal first authorship)
  1. Kothapalli CR, Van Veen JE, de Valence S, Chung S, Zervantonakis IK, Gertler FB, Kamm RD. A high-throughput microfluidic assay to study axonal response to growth factor gradients. Lab Chip, 2011, 11: 497-507.
  1. Zervantonakis IK, Kothapalli CR, Chung S, Sudo R, Kamm RD. Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments. Biomicrofluidics, 2011, 5, 1, 013406 (14 pages). Invited Article. Selected for the Virtual Journal of Nanoscale Science & Technology, 2011, 23 (14).
  1. Ibrahim S, Kothapalli CR, Kang QK, Ramamurthi A. Characterization of glycidyl methacrylate–crosslinked hyaluronan (HA) hydrogel scaffolds incorporating elastogenic HA oligomers. Acta Biomaterialia, 2011, 7(2): 653-665.
  1. Kothapalli CR, Ramamurthi A. Induced elastin regeneration by chronically-activated smooth muscle cells for targeted aneurysm repair. Acta Biomaterialia, 2010, 6(1): 170-178.
  1. Kothapalli CR, Ramamurthi A. Lysyl oxidase enhances elastin synthesis and matrix formation by vascular smooth muscle cells. J Tissue Engineering & Regenerative Medicine, 2009, 3(8): 655-661.
  1. Kothapalli CR, Gacchina CE, Ramamurthi A. Utility of hyaluronan oligomers and TGF-β1 factors for elastin matrix regeneration by aneurysmal rat aortic smooth muscle cells. Tissue Engineering Part A, 2009, 15(11): 3247-60.
  1. Kothapalli CR, Ramamurthi A. Copper nanoparticle cues for biomimetic cellular assembly of crosslinked elastin fibers. Acta Biomaterialia, 2009, 5(2): 541-553. (Top 25 downloaded articles from journal, Jan-March 2009)
  1. Kothapalli CR, Ramamurthi A. Biomimetic regeneration of elastin matrices using hyaluronan and copper ion cues. Tissue Engineering Part A, 2009, 15(1): 103-113.
  1. Kothapalli CR, Smolenski RT, Taylor PA, Yacoub MH, Ramamurthi A. TGF-β1 and hyaluronan oligomers synergistically enhance elastin matrix regeneration by vascular cells. Tissue Engineering Part A, 2009, 15(3): 501-511.
  1. Kothapalli CR, Ramamurthi A. Benefits of concurrent delivery of hyaluronan and IGF-1 cues to regeneration of crosslinked elastin matrices by adult vascular cells. J Tissue Engineering & Regenerative Medicine, 2008, 2: 106-116.
  1. Kothapalli CR, Wei M, Shaw MT. Solvent-specific gel-like transition via complexation of polyelectrolyte and hydroxyapatite nanoparticles suspended in water-glycerin mixtures: A rheological study. Soft Matter, 2008, 4: 600-605.
  1. Kothapalli CR, Shaw MT, Olson J, Wei M. Fabrication of novel calcium phosphate/ poly(lactic acid) fiber composites. J Biomed Mater Res Part B, 2008, 84B: 89-97.
  1. Kothapalli CR, Shaw MT, Wei M. Biodegradable HA-PLA porous scaffolds: Effect of nano-sized filler content on composite properties. Acta Biomaterialia, 2005, 1: 653-662. (Top 25 downloaded articles from journal, 2005-06)
  1. Kothapalli CR, Shaw MT, Wei M. Effect of operation conditions on HA synthesized by the hydrothermal method. Key Engineering Materials, 2005, 284-286: 51-54.
  1. Kothapalli CR, Wei M, Legeros RZ, Shaw MT. Influence of temperature and aging time on HA synthesized by hydrothermal method. J Materials Science: Materrials in Medicine, 2005, 16: 441-446. Invited Article
  1. Kothapalli CR, Vasiliev A, Shaw MT, Wei M. Influence of temperature and concentration on the sintering behavior and mechanical properties of hydroxyapatite. Acta Materialia, 2004, 52(19):5655-5663. (Top 25 downloaded articles from journal website, Oct-Dec 2004)
  1. Rogers RE, Kothapalli C, Lee MS, Woolsey JR. Catalysis of gas hydrates by biosurfactants in seawater-saturated sand/clay. Canadian Journal of Chemical Engineering, 2003, 81: 973-80.

 

PEER-REVIEWED BOOK CHAPTERS (*as corresponding author)
  1. Farrell K, Joshi P, Kothapalli CR*, Lee M-Y*. Neural stem cells and cellular microarray for toxicity assessment. Book title: Human Stem Cell Toxicology. Publisher: Royal Society of Chemistry, 2015. Invited Book Chapter.
  1. Joshi J, Kothapalli CR*. Current trends and future perspectives on elastic regeneration and repair approaches. Book title: Elastic Matrix: Biomimetic Regenerative Repair Approaches. Publisher: Taylor and Francis Group, 2015. Invited Book Chapter.
  1. Farrell K, Kothapalli CR*. Biomimetic materials: Polymeric substrates for axonal regeneration. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, Taylor and Francis Group, pages 913-931, 2015. Invited Book Chapter.
  1. Kothapalli CR*. Polyelectrolyte multilayers for drug-delivery applications. Handbook of Particulate Drug Delivery, Ed. M.N.V. Ravi Kumar. American Scientific Publishers, pages 91-111, 2008. Invited Book Chapter.

 

PEER-REVIEWED CONFERENCE PROCEEDINGS
  1. Srinivasan P, Zervantonakis IK, Kothapalli CR*. Theoretical and Experimental Framework of Neurite Response to Chemical Gradients in 3D Matrices. Biophysical Journal, 2014, 106 (2), p 572a.
  1. Kothapalli CR, Wei M, Shaw MT. Strength distributions of sintered hydroxyapatite nanoparticles. Proceedings of the XIth International Conference on Fracture (ICF-XI), Italy, 2005, 2: 4811-17.
  1. Kothapalli CR, Wei M, Shaw MT. Effect of temperature and concentration on hydroxyapatite morphology. 7th World Biomaterials Congress, May 17-21 2004, Sydney, Australia. Proceedings in the Transactions of 7th World Biomaterials Congress, p. 161-163.
  1. Rogers RE, Kothapalli C, Zhang G, French WT. Laboratory evidence of microbial-sediment-gas hydrate synergistic interactions in ocean sediments. Peer-reviewed Proceedings of the 14th Annual International Offshore and Polar Engineering Conference, France, 2004, 1: 41-47.
  1. Kothapalli CR, Lee MS, Rogers RE. Influence of microbes on gas hydrate formation in porous media. Proceedings of the 4th International Gas Hydrate Conference, Yokohama, Japan, May 2002, 1: 547-552.

 

CONFERENCE/ SEMINAR PRESENTATIONS
  • More than 60 presentations and posters at conferences and seminars
 
PATENTS
  • One US patent issued, and two patent applications pending