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Methods for identifying multiple DNA alteration markers in a large background of wild-type DNA

Short Description

Cancer screening by DNA analysis of clinical specimens collected from patients.

Abstract

Simultaneous determination of the alteration status of multiple DNA markers in a large background of wild-type DNA.

Inventor(s)

Dr. Baochuan Guo, Ph.D. Professor, Department of Chemistry.

Commercial Applications

  • Pre-metastasis cancer screening.

Advantages

  • Identification of multiple mutation markers in a large background of wild-type DNA.

  • Production of sufficiently pure mutant DNA fragments for determining the mutation status at a collection of DNA mutation sites in a large background of wild-type DNA.

  • Identification of methylation status of a large number of CpG sites in a large background of unmethylated DNA.

  • Produces sufficiently pure methylated DNA fragments for determining the methylation status at a collection of DNA CpG sites in a large background of unmethylated DNA.

IP Information

8,076,082

Related IP

 

Status

Licensed