Cleveland State University (CSU), hereinafter referred to as Institution, hereby gives assurance that it will comply with the Public Health Service Policy on Humane Care and Use of Laboratory Animals, hereinafter referred to as PHS Policy.
This Assurance is applicable to all research, research training, experimentation, biological
testing, and related activities, hereinafter referred to as activities, involving live, vertebrate
animals supported by the Public Health Service (PHS) and conducted at CSU, or at another
institution as a consequence of the sub-granting or subcontracting of a PHS conducted or
supported activity by this institution. There are no branches or components of this institution.
This Institution will comply with all applicable provisions of the Animal Welfare
Act and other Federal Statutes and regulations relating to animals.
This Institution is guided by the "U.S. Government Principles for the Utilization
and Care of Vertebrate Animals Used in Testing, Research, and Training."
This Institution acknowledges and accepts responsibility for the care and use of animals involved in activities covered by this Assurance. As partial fulfillment of this responsibility, this Institution will make a reasonable effort to ensure that all individuals involved in the care and use of laboratory animals understand their individual and collective responsibilities for compliance with this Assurance as well as all other applicable laws and regulations pertaining to animals care and use.
This Institution has established and will maintain a program for activities involving animals in accordance with the Guide for the Care and Use of Laboratory Animals (Guide)
Institutional Program for Animal Care and Use
The lines of authority and responsibility for administering the program and ensuring compliance with this policy are available through the Office of Sponsored Program and Research (OSPR).
The chairperson and members of the Institutional Animal Care and Use Committee
(IACUC) are appointed directly by the Vice President for Research & Graduate Studies.
At CSU, the Vice President for Research & Graduate Studies is both the Chief Executive
Officer and Institutional Official (IO). The committee is supported by staff under the
supervision of the Vice President of Research & Graduate Studies. Animal facilities at
the University are under the direction of the Vice President for Research & Graduate
Studies. The Consulting Veterinarian reports both to the Vice President for Research &
Graduate Studies in matters related to the day-to-day veterinary care of animals and to the Chairperson of the Animal Care and Use Committee for policy matters related to the
University's compliance with applicable federal regulations. The Animal Research
Facility Manager reports directly to the Director of Sponsored Programs.
The qualifications and authority of the veterinarian who will participate in the program are available through the OSPR.
This Institution has established an Institutional Animal Care and Use Committee (IACUC), which is qualified through the experience and expertise of its members to oversee the Institution's animal program, facilities, and procedures. The IACUC consists of at least five members, and its membership meets the composition requirements set forth in the PHS Policy at IV.A.3.b. A list of members is available through OSPR.
The IACUC will:
- Review at least once every six months the Institution's program for humane care and use of animals, using the Guide as a basis for evaluation.
- Inspect at least once every six months all of the Institution's animal facilities (including satellite facilities) using the Guide as a basis for evaluation.
- Prepare reports of the IACUC evaluations as set forth in the PHS Policy at IV.B.3 and
submit the reports to the Vice President of Research & Graduate Studies at Cleveland
- Review concerns involving the care and use of animals at the Institution.
- Make written recommendations to the Vice President of Research & Graduate Studies
regarding any aspect of the institution's animal program, facilities, or personnel
- Review and approve, require modifications in (to secure approval), or withhold approval of those activities related to the care and use of animals as set forth in the PHS policy at IV.C.
- Review and approve, require modifications in (to secure approval), or withhold approval of proposed significant changes regarding the use of animals in ongoing activities as set forth in the PHS Policy at IV.C.
- Notify investigators and the Institution in writing of its decision to approve or withhold approval of those activities related to the care and use of animals, or of modifications required to secure IACUC approval as set forth in the PHS Policy at IV.C.R.
- Conduct continuing review of each previously approve, ongoing activity covered by this policy at appropriate intervals as determined by the IACUC, including a complete review in accordance with the PHS Policy at IV.C. 1.-4. At least once every three years.
- Be authorized to suspend an activity involving animals as set forth in the PHS Policy at IV.C.6.
The individual(s) authorized by this Institution to verify IACUC approval of those sections of applications and proposals related to the care and use of animals is the Chairperson of the IACUC.
The health program for personnel who work in laboratory animal facilities or have frequent contact with animals is available by contacting OSPR.
Cleveland State University ensures the qualifications of those performing animal
research are adequate. High standards of professional conduct are expected of all
faculty researchers. CSU faculty members train technicians and students, both
graduate and undergraduate, in proper methods of animal anesthesia, surgery, or other
experimental manipulations. For more specialized training involving hazardous,
biological, or chemical agents, researchers may take special training at other
universities or government laboratories.
Institutional Program Evaluation and Accreditation
All of this Institution's programs and facilities (including satellite facilities) for activities
involving animals have been evaluated by the IACUC within the past six months and will
be re-evaluated by the IACUC at least once every six months thereafter, in accord with
the PHS Policy IV.B.1-2. Reports have been and will continue to be prepared in accord
with the PHS Policy IV.B.3. All IACUC semiannual reports will include a description of the nature and extent of this Institution's adherence to the "Guide." Any departures from
the "Guide" will be identified specifically and reasons for each departure will be stated.
Reports will distinguish significant deficiencies from minor deficiencies. Where program
or facility deficiencies are noted, reports will contain a reasonable and specific plan and
schedule for correcting each deficiency. Semiannual reports of the IACUC's evaluations
will be submitted to the Institutional Official. Semiannual reports of IACUC evaluations
will be maintained by this Institution and made available to the OLAW upon request.
This Institution is Category Two (2)-not accredited by the Association for Assessment
and Accreditation of Laboratory Animal Care, International (AAALAC).
Record Keeping Requirements
This Institution will maintain for at least three years:
A copy of this Assurance and any modification thereto, as approved by PHS.
Minutes of IACUC meetings, including records of attendance, activities of the committee, and committee deliberations.
Records of applications, proposals, and proposed significant changes in the care and use of animals and whether IACUC approval was given or withheld.
Records of semiannual IACUC reports and recommendations (including minority
views) as forwarded to the Vice President of Research & Graduate
Records of accrediting body determinations.
This Institution will maintain records that relate directly to applications, proposal, and proposed changes in ongoing activities reviewed and approved by the IACUC for the duration of the activity and for an additional three years after completion of the activity.
All records shall be accessible for inspection and copying by authorized OLAW or other
PHS representatives at reasonable times and in a reasonable manner.
The IACUC, through the
Institutional Official, will submit an annual report to OLAW on January 31st of each year.
The report will include:
Any change in the status of the institution (e.g., if the institution becomes accredited
by AAALAC or AAALAC accreditation is revoked), any change in the description of
the institution's program for animal care and use as described in this Assurance, or
any changes in IACUC membership. If there are no changes to the report, this
institution will provide OLAW with written notification that there are no changes.
Notification of the dates that the IACUC conducted its semiannual evaluations of the
institution's program and facilities (including satellite facilities) and submitted the
evaluations to the Vice President for Research & Graduate Studies.
The IACUC, through the Institutional Official, will provide the OLAW promptly with a
full explanation of the circumstances and actions taken with respect to:
- Any serious or continuing noncompliance with the PHS Policy.
- Any serious deviations from the provisions of the Guide.
- Any suspension of an activity by the IACUC.
Reports filed shall include any minority views filed by members of the IACUC