Center for Gene Regulation in
Health and Disease (GRHD)

Breaking News: Dr. Anton A. Komar has been appointed director of CSU’s Center for Gene Regulation in Health and Disease (GRHD). Read the full story

The Cleveland State University Center for Gene Regulation in Health and Disease focuses on research to improve understanding of biological processes and how malfunction of these processes results in various diseases. This research has significant potential to improve our understanding of the mechanisms and specific molecules that control reproductive health and those that control the aging process as well as implications for the diagnosis and treatment of many of the most common diseases found around the world, including heart disease, neurological disease, infectious disease and cancer.

Vision Statement:
To enhance and integrate research focused on Gene Regulation in Health and Disease leading to better understanding of the molecular mechanisms controlling these processes and the identification of therapeutic targets.

Mission Statement:
The Mission of the Center is:

  • To develop and support research focused on Gene Regulation in Health and Disease.
  • To encourage and provide support mechanisms for the acquisition of extramural funding.
  • To encourage and provide support mechanisms for the dissemination of research results.
  • To create mechanisms to acquire resources to support research and student training focused on Gene Regulation in Health and Disease.
  • To develop and expand partnerships with relevant public and private community entities with similar interests.
  • To develop and promote Cleveland State University’s reputation as a local, national and international leader in Gene Regulation in Health and Disease.
 
Director:  
Dr. Anton A. Komar, Professor
Translational control of gene expression and protein folding. Implications for neurodegenerative disease and drug design to treat heart disease and cancer.
Funded by AHA and HFSP (Human Frontier Science Program)
Email:: a.komar@csuohio.edu
View GRHD Lab Members
 
   
   
Planning Committee:  
Dr. Michael Kalafatis, Professor
Blood coagulation and apoptosis (cell death). Implications for heart disease and cancer.
Funded by NIH
Email: m.kalafatis@csuohio.edu
View GRHD Lab Members
 
   
Dr. Anton A. Komar, Professor
Translational control of gene expression and protein folding. Implications for neurodegenerative disease and drug design to treat heart disease and cancer.
Funded by AHA and HFSP (Human Frontier Science Program)
Email:: a.komar@csuohio.edu
View GRHD Lab Members
 
   
Dr. Barsanjit Mazumder, Professor
Regulation of inflammation. Implications for heart disease and other inflammatory diseases.
Funded by NIH and AHA
Email: b.mazumder@csuohio.edu
View GRHD Lab Members
 
   
Dr. Crystal M. Weyman, Professor
Apoptosis (cell death). Implications for heart disease, muscular dystrophy and cancer.
Funded by NIH
Email: c.weyman@csuohio.edu
View GRHD Lab Members
 
 
 
GRHD regular faculty:
 
Dr. Sailen Barik, Professor
Regulation of Cardiopulmonary Innate Immunity. Implications for lung disease and inflammatory diseases.
Funded by NIH
Email: s.barik@csuohio.edu
View GRHD Lab Members

 
 
Dr. Anthony Berdis, Assistant Professor
Funded by NIH & NSF
Email: a.berdis@csuohio.edu
View GRHD Lab Members

 
 
Dr. Valentin Boerner, Associate Professor
Mechanisms of Chromosome Segregation during Meiosis. Implications for reproductive health.
Funded by NIH, Institute of General Medicine
Email: g.boerner@csuohio.edu
View GRHD Lab Members
 
   
Dr. Roman Kondratov, Associate Professor
Circadian system regulation. Implications for aging and age-related diseases such as heart disease.
Funded by AHA and NIH
Email: r.kondratov@csuohio.edu
View GRHD Lab Members
 
   
Dr. Bibo Li, Associate Professor
Telomere (sections of DNA at the ends of chromosomes) function. Implications for infectious disease, aging and cancer.
Funded by NIH
Email: b.li37@csuohio.edu
View GRHD Lab Members
 
   
Dr. Andrew Resnick, Assistant Professor
Studies of mechanotransduction response in epithelial cells using state-of-the-art physical tools and biomarkers.
Funded by NIH
Email: a.resnick@csuohio.edu
View GRHD Lab Members
 
   
Dr. Aaron F. Severson, Assistant Professor
Mechanisms involved in the production of normal sperm and eggs. Implications for human fertility and reproductive health.
Email: a.severson@csuohio.edu
View GRHD Lab Members
 
   
Dr. Girish Shukla, Associate Professor
Regulation of mRNA processing. Implications for cancer diagnosis and treatment.
Funded by DoD
Email: g.shukla@csuohio.edu
View GRHD Lab Members
 
   

Dr. Bin Su, Assistant Professor
Design and development of novel anticancer drugs.
Funded by NIH
Email: b.su@csuohio.edu
View GRHD Lab Members

 
   
Dr. Xue-Long Sun, Professor
Antithrombotics. Implications for heart disease
Funded by NIH
Email: x.sun55@csuohio.edu
View GRHD Lab Members
 
   
Dr. Aimin Zhou, Professor
Interferon and RNase L signaling. Implications for infectious disease, heart disease and cancer.
Funded by NIH
Email: a.zhou@csuohio.edu
View GRHD Lab Members
 
engaged learning
Mailing Address
Center for Gene Regulation
in Health and Disease (GRHD)
2121 Euclid Avenue, SR 353
Cleveland, OH 44115-2214
Campus Location
2351 Euclid Avenue
Science and Research Bld., Room 353
Phone: 216-687-5580
Fax: 216.687.5549
coshp@csuohio.edu


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