Biological, Geological, and Environmental Sciences

Faculty & Research

BGES Faculty members represent a number of area institutions and are engaged in a host of different research activities. Symbols serve to indicate the institution and research area for each faculty member are explained at the bottom.

Listing of Regular and Adjunct Faculty

Name DESCRIPTORS RESEARCH INTERESTS
Alexandru Almasan

CSU
CMB

apoptosis and cell cycle control of tumor cells; genotoxic stress; radiobiology
William Baldwin CCF
CMB
cardiac and renal allograft rejection; vascular inflammation
Cornelia Bergmann CCF
CMB
regulation of and function of CD8 T cells during viral infections of the central nervous system (CNS) associated with demyelination
Kathleen L. Berkner CCF
CMB
homeostasis and the physiology of vitamin K
Meredith Bond CSU
CMB
cardiovascular pathology
G. Valentin Börner CSU
CMB
molecular genetics: functional analysis of chromosome dynamics
Tatiana Byzova CCF
CMB
Cell adhesion molecules (integrins) in thrombosis, vascular biology and cancer; vascular endothelial growth factors, angiogenesis, extracellular matrix
Pete Clapham CSU
GEO, EVS
environmental geology: geological implications of solid and hazardous waste management, Geographic Information Systems
Margot Damaser CSU
CMB

Urological Biomechanics; the nature of maternal birth injuries and the post-injury healing process; application of stem cell technology to facilitate injury recovery

R. Jeffrey Dean CSU neuroscience: motor control of limb movement & coordination in insects, amphibians, humans and robots; neuroethology: lateral line orientation; cybernetics, neural modeling & artificial neural networks
Carol De La Motte CCF
CMB

mechanisms of intestinal health and disease including inflammatory bowel disease (IBD) such as Crohn’s disease and ulcerative colitis; mechanism of bacterial protection stimulated by human milk

Rebecca Drenovsky JCU
OEB, EVS
plant-soil interface; resource availability influences on plant physiology and ecological processes; climate change, anthropogenic disturbance; invasive species
Donna Driscoll CCF
CMB
Selenoproteins and their unusual mRNA coding and translation; Selenium insufficiency and disease, including atherosclerosis, neurodegenerative diseases and cancer
Thomas Egelhoff CCF
CMB
cell migration and invasion, with emphasis on understanding the roles and regulation of myosin II; relevance to cancer cell metastasis and wound healing
Mary Gardiner
OSU
OEB
agricultural landscape ecology; invasive species; entomology; conservation of parasitoids, predators, and polinators
Brian Gastman CCF
CMB
tumor Immunology - induction of suppressor cells and immune evasion; cancer therapy resistance - oncogenes with anti-apoptotic and anti-senescent functions rendering tumors chemotherapy resistant
Michael A. Gates CSU
CMB, OEB
evolutionary biology and biometrics: morphometrics, quantitative genetics, ecology, and evolution of ciliated protists; biological pattern analysis
A. Ralph Gibson CSU
OEB
ecology, behavior and evolution: quantitative biology; thermal and reproductive biology of snakes
Neetu Gupta CCF
CMB
molecular mechanisms regulating B cell antigen receptor signaling, B cell proliferation, and fate, Role for ezrin
Stanley Hazen CCF
CMB
cell biology: biochemistry of oxidative tissue damage
Trine Joergensen CCF
CMB
autoimmunity; systemic lupus erythematosus; gender differences; role of interferons in autoimmunity
Jeffrey P. Johansen JCU
OEB , EVS
botany: ecology and systematics of algae; use of diatoms as water quality indicators; biogeography of terrestrial algae; ecology and rehabilitation of cryptogamic soil crusts
Andrew Jones CMNH
OEB, EVS
phylogeography of birds in island and mountain habitats; avian natural history
Michael Kalafatis CSU
CMB
biochemistry of blood coagulation and thrombosis
Sadashiva Karnik CCF
CMB
molecular cardiology: molecular and cellular mechanisms involved in blood pressure regulation
Anton A. Komar CSU
CMB
molecular biology: translational regulation of gene expression
Roman Kondratov CSU
CMB
molecular mechanisms of aging and circadian rhythms
Robert A. Krebs CSU
OEB, EVS
evolutionary biology: historical changes in freshwater mussel (Unionidae) distributions; models of genetic changes associated with colonization and isolation in refugia; mussel conservation
Justin Lathia CCF
CMB
tumor microenvironment and communication mechanisms used by cancer stem cells
Bibo Li CSU
CMB
molecular biology: telomere functions; pathogenesis of Trypanosoma brucei (a protozoan parasite causing sleeping sickness in humans and Nagana in cattle) in relation to telomere function and regulation of surface antigen switching to avoid immune responses
Xiaoxia Li CCF
CMB
immunology: molecular biology of interferon signaling pathways
Michelle Longworth

CCF
CMB

mechanism  of DNA organization as it pertains to proper chromosome segregation during cell division as well as the regulation of transcription relevant to development, innate immune signaling and the pathogenesis of Inflammatory Bowel Disease
Kristen Lukas CMZ

study and conservation of African apes focusing on the impact of environmental factors on behavior, the etiology of abnormal behavior, and factors influencing conservation attitudes

Barsanjit Mazumder CSU
CMB
molecular biology: molecular mechanisms of cardiovascular disease; post-transcriptional regulation of pro-inflammatory gene expression in endothelial cells, monocytes, and macrophages
Keith McCrae CCF
CMB
function of blood vessels in health and disease; antiphospholipid syndrome; microparticles--small pieces of cells that circulate in the blood, and promote blood clotting; role of kininogen in regulating vascular functions
Ronald J. Midura CCF
CMB
molecular physiology: analysis of vertebrate biomineralization mechanisms and embryonic skeletogenesis
Booki Min CCF
CMB

roles of regulatory T cells and gamma delta T cells during chronic inflammatory diseases

Barbara K. Modney CSU
CMB
neuroscience: specificity of synaptic connections during development and following injury; development of neuronal circuits and behavior
Christine S. Moravec CCF
CMB
molecular cardiology: decreased contractility in heart failure: Ca cycling, sarcoplasmic reticulum function, gene expression
Kevin Mueller

CSU
EVS, GEO

global change ecology; biodiversity; biogeochemistry; plant functional traits; land management; urban ecology; environmental pollution; paleoclimate & paleoecology; plant lipids & biomarkers (chemical fossils)  
Laura Nagy CCF
CMB
how chronic alcohol consumption contributes to chronic diseases, such as liver disease and diabetes
Edward Plow CCF
CMB

Integrin signaling in leukocyte responses during inflammation and platelet aggregation

Jun Qin CCF
CMB
structural biology: relationships between protein structure and function in cellular signal transduction pathways
Emily Rauschert CSU

Plant ecology: population and spatial dynamics, dispersal, species coexistence, biological invasions and biotic homogenization

Ofer Reizes CCF
CMB
obesity, adipose tissue development and maintenance, syndecans and heparan sulfate proteoglycan
Andrew Resnick CSU
CMB
sensory cilia in cellular mechanosensation; optical probes of matter; epithelial cell culture, electrophysiology, microscopy and laser tweezers, microfluidics and analytical modeling; renal and airway epithelial tissue
Terry L. Robison CMP
OEB, EVS
genetics, reforestation, ecosystem and pest management; influence of disturbances on ecosystem services
Tony L. Sahley CSU
CMB
auditory neurophysiology and neuropharmacology
Tobili Y. Sam-Yellowe CSU
CMB
microbiology, immunology, and parasitology: mechanisms of erythrocyte invasion in malaria; role of apical complex organelles in merozoite invasion in Plasmodium falciparum and P. chabaudi
Aaron Severson CSU
CMB
Meiosis, DNA replication, generation of sister chromatid cohesion, homolog pairing, and crossover recombination, and unique pattern of chromosome segregation
Girish Shukla CSU
CMB
Molecular Biology of RNA: in vivo and in vitro mechanisms of nuclear pre-mRNA splicing, structure-functions of small RNAs, understanding the role of miRNAs in prostate cancer, modulation of androgen receptor by miRNAs in prostate cancer
Robert H. Silverman CCF
CMB
Cancer biology: mechanism of action of interferons, particularly the role of RNase L
Jonathan D. Smith CCF
CMB
mechanisms and pathways relevant to human cardiovascular disease, such as atherosclerosis, atrial fibrillation, and HDL metabolism  
Dennis Stacey CCF
CMB
 
George Stark CCF
CMB
Molecular biology: protein and nucleic acid biochemistry, DNA amplification, molecular biology of signal transduction pathways
Olga Stenina-Adognravi CCF
CMB
Vascular complications of diabetes 
Dennis Stuehr CCF
CMB
Immunology: biology and biochemistry of nitric oxide, a molecule involved in cell signaling and host defense
Gavin Svenson CMNH

systematics and phylogenetics of the praying mantises (Mantodea)

Wilson Tang CCF
CMB

mechanistic determinants of cardiovascular disease, particular in human heart failure and cardiomyopathy

Angela H Ting CCF
CMB

mechanisms of epigenetic gene silencing and understanding the functional relevance of DNA methylation in cancer development and progression 

Bruce D Trapp CCF
CMB

cellular/molecular events involved in glial cell development and myelin formation in the central and peripheral nervous systems (CNS and PNS); pathogenic mechanisms involved in permanent neurological disability in human diseases of myelin such as Multiple Sclerosis (MS).

Vincent K. Tuohy CCF
CMB

Cancer Vaccines, Cancer Immunotherapy, Primary Immunoprevention of Breast and Ovarian Cancer

Jacqueline Vitali CSU
CMB
protein crystallography, specifically biomedically important enzymes
B. Michael Walton CSU
OEB, EVS
ecological physiology and evolutionary biology: studies of behavioral energetics, whole organism performance, and the relationship of these variables to growth and survival in natural populations of reptiles and amphibians
Crystal M. Weyman CSU
CMB
cell biology: signaling pathways regulating proliferation, differentiation, apoptosis, and transformation of skeletal myoblasts
Julie A. Wolin CSU
OEB, EVS
environmental science: diatom assemblage analysis applied to current environmental impact studies and to paleolimnological reconstructions
Riqiang Yan CCF
CMB

Alzheimer's disease (AD); developmental myelination; remyelination following injury

Qing Yi CCF
CMB

tumor immunology and immunotherapy in multiple myeloma (MM) 

Fasong Yuan

CSU
GEO, EVS

geology and environmental science: geochemical and isotopic tracers to investigate physical processes occurring in lakes and rivers, aqueous and environmental geochemistry to assess anthropogenic disturbances, environmental indicators for modern and ancient aquatic systems
Bin Zhang CCF
CMB

early secretory pathway deficiencies in human diseases such as hemophilia A and cancer

HOME INSTITUTION RESEARCH AREA
  • CSU - Cleveland State University
  • CCF -  Cleveland Clinic Foundation
  • CWRU - Case Western Reserve University
  • JCU - John Carroll University
  • CBG - Cleveland Botanical Garden
  • CMP - Cleveland Metroparks
  • CMZ - Cleveland Metroparks Zoo
  • CMNH - Cleveland Museum of Natural History
  • CMB - Cell and Molecular Biology
  • OEB - Organismal and Evolutionary Biology
  • GEO - Geology
  • EVS - Environmental Science


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