Cleveland State University

Technology Transfer Office

Available Technologies - Abstract

Title

Methods for identifying multiple DNA alteration markers in a large background of wild-type DNA.

Short Description Cancer screening by DNA analysis of clinical specimens collected from patients.
Abstract Simultaneous determination of the alteration status of multiple DNA markers in a large background of wild-type DNA.
Inventor(s) Dr. Baochuan Guo, Ph.D. Professor, Department of Chemistry.
Commercial Applications
  • Pre-metastasis cancer screening.
Advantages
  • Identification of multiple mutation markers in a large background of wild-type DNA.
  • Production of sufficiently pure mutant DNA fragments for determining the mutation status at a collection of DNA mutation sites in a large background of wild-type DNA.
  • Identification of methylation status of a large number of CpG sites in a large background of unmethylated DNA.
  • Produces sufficiently pure methylated DNA fragments for determining the methylation status at a collection of DNA CpG sites in a large background of unmethylated DNA.
IP Information 8,076,082
Related IP


Status Licensed
engaged learning
  • Partners
Campus Location
Parker Hannifin Hall, 214
2258 Euclid Avenue
Cleveland, OH 44115
Phone: 216.687.5108
This site contains files that require the free Adobe Reader to view.