Cleveland State University
Sponsored Programs and Research Services
Recombinant DNA Exemption Certification
I, _______________________ certify that the experiments outlined
in my proposal entitled, _________________________________________________________________
are exempt from review by and registration with the Institutional
Biosafety Committee (IBC) because: (Check all that apply.)
- the experiments are not in organisms or viruses.
- the experiments consist entirely of DNA segments from a single
nonchromosomal or viral DNA source.
- the experiments consist entirely of DNA from a prokaryotic
host including its indigenous plasmids or viruses when propagated
only in that host (or a closely related strain of the same species),
or when transferred to another host by well established physiological
- the experiments consist entirely of DNA from an eukaryotic
host including its chloroplasts, mitochondria, or plasmids (but,
excluding viruses) when propagated only in that host (or closely
related strain of the same species).
- the experiments consist entirely of DNA segments from different
species that exchange DNA by known physiological processes, though
one or more of the segments may be a synthetic equivalent. (See
Appendix A of NIH Guidelines for lists of such exchangers.)
- the experiments do not present a significant risk to health
or the environment. (See Appendix C of NIH Guidelines for exempt
classes of experiments.)
Principal Investigator: Typed
or Printed Name
Department Chair: Typed or Printed
If your work with recombinant DNA cannot be excluded from
review under these exempt categories, then your experiments must
be reviewed by and registered with the IBC.