Academics at Fenn College of Engineering: Doctoral Program in Applied Biomedical Engineering

Program Requirements

medical devicesAll graduates gain depth of knowledge and understanding of the fundamentals of biomedical engineering, via the core curriculum:

• CHE 751 Biomechanical Engineering
• CHE 753 Tissue Engineering
• CHE 757 Medical Devices and Biomaterials
• CHE 759 Medical Imaging
• College Level Physiology

A strong foundation in engineering mathematics is provided by selection of two advanced math courses.

World-class experts in the field teach electives in biomedical engineering. To complement the wide variety of research areas, a sample of available electives include:
• 3D Kinematics
• Tissue Mechanics
• Artificial Organs
• Pathophysiology of Diabetes
• BioMEMS
• Experimental Methods in Biomedical Engineering
• Biopolymers
• Advanced Tissue Engineering
• Vascular Bioengineering

In addition, advanced courses in mathematics, biology, chemistry, physics and traditional engineering disciplines are offered.

Students who are interested in engineering solutions to the disease diabetes may choose to participate in the DIABET (Diabetes Initiative for Applied Biomedical Engineering Technologies) track within the ABE program (described on back).

Duration of Study:

A minimum of 61 credits is required for the DRE degree, including 31 credits of coursework and 30 credits of research/dissertation. The DRE degree typically takes four years of full time effort to complete.

Examinations:

There are three examinations in the DRE program: qualifying, candidacy and dissertation defense.

The qualifying exam will evaluate a prospective student’s mastery of fundamental subject matter specific to the chosen engineering discipline/concentration beyond what is demonstrated by prior grades. The examination is administered in May of the first year of Doctoral studies and must be successfully completed before a student exceeds 20 credit hours beyond the master’s degree.

The purpose of the candidacy examination is to assess maturity and preparation to perform independent research in a specific topic. The exam will be taken in a period not to exceed two years after successful completion of the qualifying exam.

The dissertation is a concentrated, in-depth, independent study of an appropriate engineering problem. The dissertation defense involves a public seminar, followed by an in-depth oral examination by the student's advisory committee.

Other Requirements:

All students are expected to attend departmental seminars. Beginning in the second year of study, students are expected to present research progress in a seminar semi-annually.

Core Competency:

Students are expected to have a strong foundation in an engineering discipline, or in sciences, or in medicine through their BS and MS degrees before entering ABE.

A working knowledge of college level Physiology is required for all students. If taken at the graduate level, Physiology may count as an elective.

Core Courses

For up to date information on courses please visit the Applied Biomedical Engineering course listing under graduate catalog.

CHE 751 Biomechanical Engineering
Instructors: B. Davis, PhD / G.Chatzimavroudis, PhD

Understanding terms, concepts and interdisciplinary nature of biomechanical engineering as it relates to basic and applied and how it relates to medical needs and patients. Prerequisites: doctoral standing in Engineering College or permission of Instructor.
CHE 753 Tissue Engineering
Instructor: N.Holland, PhD

Essential concepts and technologies in cellular and molecular biology, as relevant to the design, application and evaluation of biological constructs in tissue engineering with preliminary understanding of commercial applications. Prerequisites: doctoral standing in Engineering College or permission of Instructor.
CHE 757 Medical Device Design and Biomaterials Instructor: N.Holland, PhD

An overview of design and regulatory issues surrounding the development of medical devices with emphasis on the role of biomaterials and the physiologic responses to implantation. Prerequisites: doctoral standing in Engineering College or permission of Instructor.
CHE 759 Medical Imaging
Instructor: G.Chadtzimavroudis, PhD

Introduction to signal processing, Tomographic reconstruction techniques, Ultrasound, Radionuclide imaging and MRI. Prerequisites: doctoral standing in Engineering College or permission of Instructor and college level physiology.

Required Engineering Mathematics


ESC 702 Applied Engineering Analysis I
Instructor: Staff, CSU

Methods of optimization for engineering systems; classical optimization, Taylor’s theorem, Lagrange multipliers, and Kuhn-Tucker Theorem; direct methods, Newton and quasi-Newton methods, penalty and barrier methods, linear and non-linear programming.
ESC 704 Applied Engineering Analysis II
Instructor: Staff, CSU

Optimization in engineering economics; application of renewal theory; inventory ad Markov decision models, Bayesian decision analysis.
ESC 704 Applied Engineering Analysis III
Instructor: Staff, CSU

Engineering applications and solution techniques for partial differential equations; variational derivation of differential equations and boundary conditions; Hamilton’s principle and Lagrange’s equation; numerical methods and computer solutions for differential equations.

ABE Electives 

All 700-level graduate engineering courses can be used as an elective (a maximum of one course at 500-level is permitted). A list of approved courses from departments outside the engineering college will be available to help in the preparation of the program of study. 

Although students are encouraged to take courses in their research area or for their personal interest, courses not appearing in the study plan cannot be used as electives to satisfy the minimum degree requirements. At least one elective course in biomedical engineering is offered each semester. 

Courses include: 

Biofluid Mechanics

Experimental Methods for Biomedical Engineering

3D Kinematics

Tissue Mechanics

Artificial Organ/Pancreas Design

Cardiovascular Bioengineering

Pathophysiology of Diabetes

Tissue Viscoelasticity

Obesity and Related Disorders

Micro-electro-mechanical systems (MEMS)

CHE-794-02 Tissue Mechanics Instructors: Drs. Rashidi/ Derwin

Biology,structure, and mechanics of several musculoskeletal tissues including: bone, tendon and ligament, cartilage, and meniscus. Integrating the anatomy and biology with the structural and mechanical behavior of these tissues and the role of mechanics in the adaptation, injury, and repair of these biologic tissues. Experimental methods and constitutive models for assessing tissue mechanical behavior. Prerequisites: doctoral standing in Engineering College or permission of Instructor and college level physiology.
CHE 794-01 Experimental Methods for Biomedical Engineering Instructor: Drs. Chatzimavroudis/ Davis

The study of rigid body motions, analyses of forces and moments. Fundamental concepts of motions in the context of understanding normal and abnormal skeletal mechanics. Methodologies for quantifying angular displacements and velocities, including screw axis, Euler and Cardan angles. Discussions of kinematic theories, landmark papers reviews. Experimental Design, data acquisition, processing, and analysis with parametric and non-parametric statistical methods. Prerequisites: doctoral standing in Engineering College or permission of Instructor and college level statistics.
CHE 794-05 3D Kinematics
Instructor: Dr. Davis

Exploration of data equipment and techniques for data collection methods; processing and analysis of biophysical signals. Overview of theoretical and practical concerns of measuring biological and mechanical variables. Statistical planning of experiments, parametric and non-parametric statistical analyses, error analyses, and data normalization. Prerequisites: doctoral standing in Engineering College or permission of Instructor.
CHE 794-06 Biofluid Mechanics
Instructor: Dr. Chatzimavroudis

Overview of biofluid flow of the cardiovascular system under various material properties and conditions. Prerequisites: doctoral standing in Engineering College or permission of Instructor and college level physiology.
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Mailing Address
Chemical and Biomedical Engineering Department
Fenn College of Engineering
Cleveland State University
2121 Euclid Ave., SH 455
Cleveland, Ohio 44115-2214
Campus Location
Stilwell Hall Room 455
1980 East 24th Street
Phone: 216.687.2569
Fax: 216.687.9220
ChE@csuohio.edu
Contact
Jorge E. Gatica
j.gatica@csuohio.edu
Phone: 216.523.7274


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